SUSTIVA is a prescription medicine used in combination with other medicines to treat HIV-1 infection. In HIV combination therapy, SUSTIVA
can help lower
to undetectable* and has been shown to help improve
the body’s immune system by raising
(T-cell) counts. SUSTIVA may not have these effects in every patient. SUSTIVA does not cure HIV or AIDS. You must keep taking HIV medicines in order to control HIV infection and decrease HIV-related illnesses.
Do not take SUSTIVA if you are allergic to the active ingredient, efavirenz, or to any of the inactive ingredients. Your doctor and pharmacist have a list of the inactive ingredients.
SUSTIVA® (efavirenz) is a prescription medicine used with other antiretroviral medicines to help treat HIV-1 infection in adults and children 3 months or older and who weigh at least 3.5 kg (7 lbs 12 oz).
SUSTIVA does not cure HIV or AIDS. You must keep taking HIV medicines in order to control HIV infection and decrease HIV-related illnesses.
Do not take SUSTIVA if you are allergic to efavirenz or any of the ingredients.
Before taking SUSTIVA, tell your doctor if you:
You should not become pregnant and must use two effective forms of birth control while taking SUSTIVA and for
12 weeks after stopping it. A barrier form of birth control such as a condom, contraceptive sponge, diaphragm with
spermicide, and cervical cap must be used along with another type of birth control. Hormonal forms of birth control,
such as birth control pills, injections, vaginal rings, or implants may not work during treatment with SUSTIVA.
Tell your doctor about all the medicines you take, including prescription and over the counter medicines, vitamins, and herbal supplements.
SUSTIVA may affect the way other medicines work and other medicines may affect how SUSTIVA works, and may cause serious side effects.
You should not take SUSTIVA if you take ATRIPLA (efavirenz, emtricitabine, tenofovir disoproxil fumarate) unless your doctor tells you to.
The following medicines may need to be replaced with another medicine during your treatment with SUSTIVA:
boceprevir (Victrelis®), carbamazepine (Carbatrol®, Tegretol®, Tegretol-XR®, Equetro®, Teril®, Epitol®), clarithromycin
(Biaxin®, Biaxin XL®), itraconazole (Sporanox®, Onmel®), posaconazole (Noxafil®), saquinavir mesylate (Invirase®),
Please refer to the Patient Information for a list of medicines that may require a change in the dose of either SUSTIVA or the other medicine.
Know the medicines you take. Keep a list of your medicines and show it to your doctor and pharmacist when you
get a new medicine.
SUSTIVA may cause serious side effects, including:
The most common side effects with SUSTIVA include: rash, dizziness, nausea, headache, difficulty concentrating,
abnormal dreams, tiredness, trouble sleeping, and vomiting.
Some patients have experienced increase levels of lipids (cholesterol and triglyceride) in the blood. Tell your doctor if you
have any side effect that bothers you or that does not go away.
You should take SUSTIVA on an empty stomach, preferably at bedtime, which may make some side effects less bothersome.
US Full Prescribing Information